Forensic Chemistry and Biochemistry

Applications of desi-ms in Forensic Analysis

DESI-MS (desorption electrospray ionisation mass spectrometry) is an ambient ionisation technique with a lot of potential in forensic chemistry. The method allows for fast in-situ analyses without the need for lengthy sample preparation. In the literature, several DESI-MS applications in forensics, medical diagnostics, and food control have already been published. The research summarises the most recent DESI-MS forensic applications in the examination of biological fluids and tissues, such as fingerprints, skin, urine, and blood, which have sparked increased interest in recent years. The study focuses on determining the presence of medicines and illicit drugs in biological fluids and tissues, where DESI-ability MS's for screening and drug detection has been established.