Recent advancements in sample preparation and extraction methods in forensic analysis

In forensic analytical toxicology, sample preparation is crucial. Various extraction methods are used to remove interferences from biological samples including blood, tissues, and hair, reduce matrix effects, and concentrate the target analytes, among other things. Microextraction techniques have been expanding their applications in recent years with the aim of creating quicker and more environmentally friendly procedures.  Solid-based microextraction methods, such as solid-phase microextraction, microextraction by packed sorbent, and stirbar sorptive extraction, as well as liquid-based microextraction methods, such as single drop/hollow fiber-based liquid-phase microextraction and dispersive liquid–liquid microextraction, are used in forensic toxicology analysis.

  • Microextraction methods
  • Solid‐phase microextraction
  • liquid‐based microextraction

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